(Wired) – Today, things are looking a little less mysterious. A team of researchers led by neuroscientists at UC San Francisco has spent the last five years compiling the first entries in what they hope will become an extensive atlas of gene expression in the developing human brain. The researchers describe the project in the latest issue of Science, and, with the help of researchers at UC Santa Cruz, they’ve made an interactive version of the atlas freely available online.
(International Business Times) – The investigation into Libya’s seedy underbelly, where men and women are sold off to the highest bidder, has earned international condemnation, with demands for a swift investigation into the human rights atrocity. Now, a Ghanaian lawyer claims trafficking in the country is being used to facilitate the illegal sale of human organs and encourage a lucrative “red market”.
The New England Journal of Medicine (vol. 377, no. 8, 2017) is available online by subscription only.
- “From Last to First — Could the U.S. Health Care System Become the Best in the World?” by E.C. Schneider and D. Squires
- “The HITECH Era and the Path Forward” by V. Washington, K. DeSalvo, F. Mostashari, and D. Blumenthal
- “The HITECH Era in Retrospect” by J.D. Halamka and M. Tripathi
- The Changing Face of Clinical Trials: Randomized, Controlled Trials in Health Insurance Systems” by N.K. Choudhry
Clinical Ethics (vol. 12, no. 3, 2017) is available online by subscription only.
- “The Ethical Basis for Performing Cardiopulmonary Resuscitation Only After Informed Consent in Selected Patient Groups Admitted to Hospital” by Philip Berry and Iona Heath
- “Is Healthcare Providers’ Value-Neutrality Depending on how Controversial a Medical Intervention Is? Analysis of 10 More or Less Controversial Interventions” by Niels Lynöe, Joar Björk, and Niklas Juth
- “Attitudes of Singapore Emergency Department Staff Towards Family Presence During Cardiopulmonary Resuscitation” by Zohar Lederman et al.
- “‘It’s Like Sailing’ – Experiences of the Role as Facilitator During Moral Case Deliberation” by Dara Rasoal, Annica Kihlgren, and Mia Svantesson
- “Overruling Parental Decisions in Paediatric Medicine: A Comparison of Diekema’s Harm Threshold Framework and the Zone of Parental Discretion Framework” by Vicki Xafis
- “Beyond Individualism: Is There a Place for Relational Autonomy in Clinical Practice and Research?” by Edward S Dove et al.
JAMA (vol. 318, no. 9, 2017) is available online by subscription only.
- “The Nuremberg Code 70 Years Later” by Jonathan D. Moreno, Ulf Schmidt, and Steve Joffe
- “Correcting the Medical Literature: ‘To Err Is Human, to Correct Divine'” by Stacy Christiansen and Annette Flanagin
- “Change in Medical Exemptions From Immunization in California After Elimination of Personal Belief Exemptions” by Paul L. Delamater, Timothy F. Leslie, and Y. Tony Yang
JAMA Internal Medicine (vol. 177, no. 9, 2017) is available online by subscription only.
- “Sharing as the Future of Medicine” by Richard Lehman
- “Shared Decision Making—The Importance of Diagnosing Preferences” by Glyn Elwyn, Nan Cochran, and Michael Pignone
- “Sharing Clinical Research Data—Finding the Right Balance” by Bernard Lo and Steven N. Goodman
- “Sharing Knowledge for Health Care” by Tammy Hoffmann and Sharon Straus
- “Sharing the Process of Diagnostic Decision Making” by John E. Brush Jr and James M. Brophy
- “Shared Understanding With Patients” by Neal Maskrey and Andrea Gordon
- “Sharing Experiences of Illness and Care” by Louise Locock, Richard Lehman, and Ronald M. Epstein
- “Medical Assistance in Dying: Our Lessons Learned” by Kieran L. Quinn and Allan S. Detsky
British Medical Bulletin (vol. 123, no. 1, 2017) is available online by subscription only.
- “Think Adult – Think Child! Why Should Staff Caring for Dying Adults Ask What the Death Means for Children in the Family?” by Norman Vetter
- “Physician-Assisted Suicide—A Clean Bill of Health?” by Robert Preston
(Reuters) – The U.S. Food and Drug Administration on Thursday cleared a device embedded in an Apple Inc watch band that monitors a user’s heart rate, detects when something is amiss and prompts the user to take an electrocardiogram. The device, made by AliveCor, pairs the ability to take a personal 30 second electrocardiogram (EKG) with a feature that uses artificial intelligence to continuously evaluate the correlation between heart and physical activity.
(STAT News) – A new Chatham House paper that I co-authored with Tom Brookes and Eloise Whitaker shows that up to hundreds of thousands of people are detained in hospitals against their will each year. Their crime? Being too poor to pay their medical bills. This phenomenon is particularly prevalent in several sub-Saharan African countries, notably Nigeria, Democratic Republic of Congo, Ghana, Cameroon, Zimbabwe, and Kenya, but there is also evidence of it in India and Indonesia. The practice of medical detentions is particularly rife in Democratic Republic of Congo. In one study of a health facility over a six-week period in 2016, 54 percent of women who had given birth and were eligible for discharge were detained for the nonpayment of user fees.
(NPR) – Beautiful. Pure. Natural. Medicine at its pinnacle. Those were the words of Dr. Giuliano Testa this week — the principal investigator of a clinical trial with ten women underway at Baylor University Medical Center in Dallas. He was talking about the birth of a baby boy to a mother who underwent a uterus transplant last year. It’s a first in the U.S., but in Sweden, eight babies have been born to mothers with uterus transplants. Not everyone is celebrating though.
(New York Times) – The cobbler’s desperate need exemplifies a problem that deeply worries palliative care experts: how they can help the 25 million people who die in agony each year in poor and middle-income countries without risking an American-style overdose epidemic abroad or triggering opposition from Western legislators and philanthropists for whom “opioid” has become a dirty word.
(Kaiser Health News) – It may not be rocket science, but a group of surgeons at the University of Michigan’s Michigan Medicine have devised a strategy to curb the nation’s opioid epidemic — starting at their own hospital. Their findings appeared online Wednesday in the journal JAMA Surgery. Opioid addiction has been deemed a “national emergency.” It’s estimated to have claimed 64,000 lives in 2016 alone. And research shows that post-surgical patients are at an increased risk of addiction because of the medication they receive to help manage pain during recovery.
(Washington Post) – After years of debate, the organization that oversees the allocation of livers for transplant took steps Monday to address a long-standing geographic disparity in supply of the scarce organs. The policy approved by the Organ Procurement and Transplantation Network will make more livers available in some places — including cities such as New York and Chicago — where the shortage is more severe than it is in regions such as the southeastern United States.
(New York Times) – I have been a wheelchair user since early childhood, when I sustained a spinal cord injury in a farming accident. I am now a practicing physician in the field of rehabilitation and sports medicine. In my busy outpatient clinical practice, I witness the spectrum of patients’ reactions when they find out that their doctor is, herself, disabled. Typically those first few seconds after entering an exam room — before the patient’s guard goes up — are the most informative.
Journal of Genetic Counseling (vol. 26, no. 5, 2017) is available online by subscription only.
- “A Systematic Review of Randomized Controlled Trials to Assess Outcomes of Genetic Counseling” by Barbara A. Athens et al.
- “Characterizing Clinical Genetic Counselors’ Countertransference Experiences: an Exploratory Study” by Rebecca Reeder et al.
- “Reasons for Declining Preconception Expanded Carrier Screening Using Genome Sequencing” by Marian J. Gilmore et al.
- “Experiences of Pre-Implantation Genetic Diagnosis (PGD) in Sweden: a Three-Year Follow-Up of Men and Women” by Stina Järvholm, Ann Thurin-Kjellberg, and Malin Broberg
- “Attitudes Towards Prenatal Genetic Counseling, Prenatal Genetic Testing, and Termination of Pregnancy among Southeast and East Asian Women in the United States” by Ginger J. Tsai et al.
- “Genetic Counselors’ Perception of the Effect on Practice of Laws Restricting Abortion” by Caitlin Cooney, Laura Hercher, and Komal Bajaj
- “Should Genetic Testing be Offered for Children? The Perspectives of Adolescents and Emerging Adults in Families with Li-Fraumeni Syndrome” by Melissa A. Alderfer et al.
The Linacre Quarterly (vol. 84, no. 3, 2017) is available online by subscription only.
- “A Guide for Religious for End-of-Life Decision Making” by Fr. James McTavish
- “Is Medicine Losing Its Way? A Firm Foundation for Medicine as a Real
Therapeia” by Willem Jacobus Cardinal Eijk
- “Spiritual Care of the Sick” by Fr. Juan R. Vélez
- “Why the Moratorium on Human-Animal Chimera Research Should Not Be
Lifted” by Alan Moy
- “Decision Making in Neonatal End-of-Life Scenarios in Low-Income
Settings” by Fr. James McTavish
- “Pulmonary Hypertension: Clinical Parameters of a Difficult Case in
Pregnancy” by Byron C. Calhoun
- “Moral Theological Analysis of Direct Versus Indirect Abortion” by John M. Haas
- “Hormonal Contraception and the Development of Autoimmunity: A Review
of the Literature” by William V. Williams
Journal of Bioethical Inquiry (vol. 14, no. 3, 2017) is available online by subscription only.
- “Stretching the Boundaries of Parental Responsibility and New Legal Guidelines for Determination of Brain Death” by Bernadette Richards and Thaddeus Mason Pope
- “Futile Treatment—A Review” by Lenko Šari?, Ivana Prki? and Marko Juki?
- “Are Wrongful Life Actions Threatening the Value of Human Life?” by Vera Lúcia Raposo
- “Political Minimalism and Social Debates: The Case of Human-Enhancement Technologies” by Javier Rodríguez-Alcázar
- “Including People with Dementia in Research: An Analysis of Australian Ethical and Legal Rules and Recommendations for Reform” by Nola M. Ries, Katie A. Thompson, and Michael Lowe
- “Measles Vaccination is Best for Children: The Argument for Relying on Herd Immunity Fails” by Johan Christiaan Bester
- “Medical Negligence Determinations, the “Right to Try,” and Expanded Access to Innovative Treatments” by Denise Meyerson
- “Access to High Cost Cancer Medicines Through the Lens of an Australian Senate Inquiry—Defining the “Goods” at Stake” by Narcyz Ghinea, Miles Little, and Wendy Lipworth
- “Exploring Vaccine Hesitancy Through an Artist–Scientist Collaboration” by Kaisu Koski and Johan Holst
- “A Feminist Critique of Justifications for Sex Selection” by Tereza Hendl
Medico-Legal Journal (vol. 85, no. 3, 2016) is available online by subscription only.
- “Liability for Providing a Prognosis in Surgical Practice” by Alex de Costa and Amy Tam
- “Judicial Oversight of Life-Ending Withdrawal of Assisted Nutrition and Hydration in Disorders of Consciousness in the United Kingdom: A Matter of Life and Death” by Mohamed Y Rady and Joseph L. Verheijde
The New England Journal of Medicine (vol. 377, no. 9, 2017) is available online by subscription only.
- “Interprofessional Education — A Foundation for a New Approach to Health Care” by A. Dow and G. Thibault
- “Abandonment” by R. Srivastava
(Vox) – There are 141 million visits to the emergency room each year, and nearly all of them (including Saifan’s) have a charge for something called a facility fee. This is the price of walking through the door and seeking service. It does not include any care provided. Emergency rooms argue that these fees are necessary to keep their doors open, so they can be ready 24/7 to treat anything from a sore back to a gunshot wound. But there is also wide variation in how much hospitals charge for these fees, raising questions about how they are set and how closely they are tethered to overhead costs.