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A New Edition of Journal of Medical Ethics Is Now Available

Mon, 12/04/2017 - 09:00

Journal of Medical Ethics (vol. 43, no. 9, 2017) is available online by subscription only.

Articles include:

  • “The Ethics Liaison Program: Building a Moral Community” by Sarah R Bates et al.
  • “Organ Donation After Medical Assistance in Dying or Cessation of Life-Sustaining Treatment Requested by Conscious Patients: The Canadian Context” by Julie Allard and Marie-Chantal Fortin
  • “Teaching, Learning and Assessment of Medical Ethics at the UK Medical Schools” by Lucy Brooks and Dominic Bell
  • “Ethical Questions Identified in a Study of Local and Expatriate Responders’ Perspectives of Vulnerability in the 2010 Haiti Earthquake” by Evelyne Duroche et al.
  • “3D Bioprint Me: A Socioethical View of Bioprinting Human Organs and Tissues” by Niki Vermeulen et al.
  • “Vaccine Testing for Emerging Infections: The Case for Individual Randomisation” by Nir Eyal and Marc Lipsitch
  • “Eliminating Latent Tuberculosis in Low-Burden Settings: Are the Principal Beneficiaries to be Disadvantaged Groups or the Broader Population?” by Chris Degeling et al.
  • “How Shared Is Shared Decision-Making? A Care-Ethical View on the Role of Partner and Famil” by Inge van Nistelrooij et al.
  • “Designing Methuselah: An Ethical Argument Against Germline Genetic Modification to Prolong Human Longevity” by Isabelle L Robertson


A New Edition of Neuroethics Is Now Available

Mon, 12/04/2017 - 09:00

Neuroethics (vol. 10, no. 3, 2017) is available online by subscription only.

Articles include:

  • “Deep Brain Stimulation Through the “Lens of Agency”: Clarifying Threats to Personal Identity from Neurological Intervention” by Eliza Goddard
  • “From ‘Hard’ Neuro-Tools to ‘Soft’ Neuro-Toys? Refocussing the Neuro-Enhancement Debate” by Jonna Brenninkmeijer and Hub Zwart
  • “Does Kantian Ethics Condone Mood and Cognitive Enhancement?” by Robert R. Clewis
  • “Moral Enhancement Should Target Self-Interest and Cognitive Capacity” by Rafael Ahlskog
  • “The Multiplicity of Memory Enhancement: Practical and Ethical Implications of the Diverse Neural Substrates Underlying Human Memory Systems” by Kieran C. R. Fox, Nicholas S. Fitz, and Peter B. Reiner
  • “Towards a Moral Ecology of Pharmacological Cognitive Enhancement in British Universities” by Meghana Kasturi Vagwala et al.
  • “Public Attitudes Towards Moral Enhancement. Evidence that Means Matter Morally” by Jona Specker, Maartje H. N. Schermer, and Peter B. Reiner


A New Edition of JAMA Is Now Available

Mon, 12/04/2017 - 09:00

JAMA (vol. 318, no. 8, 2017) is available online by subscription only.

Articles include:

  • “Gene Editing Using CRISPR: Why the Excitement?” by Anthony L. Komaroff
  • “Time for Transparent Standards in Quality Reporting by Health Care Organizations” by Peter J. Pronovost, Albert W. Wu, and J. Matthew Austin
  • “Multidimensional Evidence Generation and FDA Regulatory Decision Making: Defining and Using “Real-World” Data” by Jonathan P. Jarow, Lisa LaVange, and Janet Woodcock


A New Edition of The New England Journal of Medicine Is Now Available

Mon, 12/04/2017 - 09:00

The New England Journal of Medicine (vol. 377, no. 8, 2017) is available online by subscription only.

Articles include:

  • “Threats to Information Security — Public Health Implications” by W.J. Gordon, A. Fairhall, and A. Landman
  • “Man versus Nature — Also Sprach Zarathustra and an End-of-Life House Call” by M.M. Krem


A New Edition of The American Journal of Bioethics Is Now Available

Mon, 12/04/2017 - 09:00

The American Journal of Bioethics (vol. 17, no. 9, 2017) is available online by subscription only.

Articles include:

  • “A Bridge Back to the Future: Public Health Ethics, Bioethics, and Environmental Ethics” by Lisa M. Lee
  • “Now is the Time for a Postracial Medicine: Biomedical Research, the National Institutes of Health, and the Perpetuation of Scientific Racism” by Javier Perez-Rodriguez and Alejandro de la Fuente


AI-Controlled Brain Implants for Mood Disorders Tested in People

Fri, 12/01/2017 - 12:22

(Nature) – Brain implants that deliver electrical pulses tuned to a person’s feelings and behaviour are being tested in people for the first time. Two teams funded by the US military’s research arm, the Defense Advanced Research Projects Agency (DARPA), have begun preliminary trials of ‘closed-loop’ brain implants that use algorithms to detect patterns associated with mood disorders. These devices can shock the brain back to a healthy state without input from a physician. The work, presented last week at the Society for Neuroscience (SfN) meeting in Washington DC, could eventually provide a way to treat severe mental illnesses that resist current therapies. It also raises thorny ethical concerns, not least because the technique could give researchers a degree of access to a person’s inner feelings in real time.

More States Hatch Plans to Recycle Drugs Being Wasted in Nursing Homes

Fri, 12/01/2017 - 12:16

(Pro Publica) – ProPublica’s story detailed how the nursing home industry dispenses medication a month at a time, but then is forced to destroy it after patients pass away, stop using it or move out. Some send the drugs to massive regional incinerators or flush them down the toilet, creating environmental concerns. In Iowa, a program called SafeNetRx retrieves the excess medication, inspects it and dispenses it for free to needy patients. Almost 80,000 Iowans have used SafeNetRx to obtain medication — from cheap antibiotics to cancer drugs worth thousands of dollars per month.

Philippines Suspends Dengue Shots after Drug Firm’s Warning

Fri, 12/01/2017 - 12:12

(New York Times) – The Philippines suspended its school-based dengue immunization program on Friday after the French pharmaceutical giant Sanofi warned that its flagship vaccine, Dengvaxia, had been found to pose health risks in people not previously infected. The suspension came after health experts expressed worries about Sanofi’s announcement this week. The company said further clinical studies had revealed that, in those who had previously had dengue, the vaccine could prevent repeat infection. But for those who had not had dengue, and were vaccinated and later became infected, “more cases of severe disease could occur,” Sanofi said in the advisory.

Brain Organoids Get Cancer, Too, Opening a New Frontier in Personalized Medicine

Fri, 12/01/2017 - 12:05

(STAT News) – In the barely three years since biologists discovered how to create these “brain organoids,” the lentil-sized structures have taken neuroscience by storm. Starting with a recipe developed by scientists in Austria, researchers from Japan and China to Europe and North America are seeding lab dishes with human stem cells, adding special molecules — many labs, like chili chefs, have their own secret blends — that make the stem cells morph into a variety of brain cells. They then put the dishes into special chambers called bioreactors that keep them warm and in gentle motion reminiscent of a womb, encouraging the cells to form blobs with working neurons and many other features of a full-size human brain.

FDA Approves First-of-a-Kind Test for Cancer Gene Profiling

Fri, 12/01/2017 - 11:57

(Medical Xpress) – U.S. regulators have approved a first-of-a-kind test that looks for mutations in hundreds of cancer genes at once, giving a more complete picture of what’s driving a patient’s tumor and aiding efforts to match treatments to those flaws. The U.S. Food and Drug Administration approved Foundation Medicine’s test for patients with advanced or widely spread cancers, and the Centers for Medicare and Medicaid Services proposed covering it.

New Vaccine, Long-Acting Drug Trial Buoy Hopes in HIV Fight

Fri, 12/01/2017 - 11:43

(Reuters) – Researchers announced the launch of two big studies in Africa on Thursday to test a new HIV vaccine and a long-acting injectable drug, fuelling hopes for better ways to protect against the virus that causes AIDS.  The start of the three-year vaccine trial involving 2,600 women in southern Africa means that for the first time in more than a decade there are now two big HIV vaccine clinical trials taking place at the same time.

Early Embryos Kept in Check

Fri, 12/01/2017 - 11:38

(Nature) – Shahbazi et al. used their ex utero culture systems to study the coordination between the exit from pluripotency and the formation of the amniotic cavity. First, the authors noticed that the downregulation of pluripotency genes coincided with the appearance of the amniotic cavity in both mouse and human embryos. Next, they observed that maintaining pluripotent cells in a naive state in embryos by artificially supplying LIF prevented the cells from forming the amniotic cavity.

Unconscious Patient with ‘Do Not Resuscitate’ Tattoo Causes Ethical Conundrum at Hospital

Fri, 12/01/2017 - 10:51

(Gizmodo) – But with the “DO NOT RESUSCITATE” tattoo glaring back at them, the ICU team was suddenly confronted with a serious dilemma. The patient arrived at the hospital without ID, the medical staff was unable to contact next of kin, and efforts to revive or communicate with the patient were futile. The medical staff had no way of knowing if the tattoo was representative of the man’s true end-of-life wishes, so they decided to play it safe and ignore it.

A New Edition of Zygon Journal of Religion and Science Is Now Available

Fri, 12/01/2017 - 09:00

Zygon Journal of Religion and Science (vol. 52, no. 3, 2017) is available online by subscription only.

Articles include:

  • “Transhumanism, Theological Anthropology, and Modern Biological Taxonomy” by Travis Dumsday
  • “A Contribution to the Debate on Science and Faith by Christian Students from Abidjan” by Klaas Bom And Benno Van Den Toren
  • “Should a Christian Adopt Methodological Naturalism?” by Andrew B. Torrance
  • “Assessing the Field of Science and Religion: Advice from the Next Generation” by Michael S. Burdett
  • “Philosophical Anthropology, Ethics, and Love: Toward a New Religion and Science Dialogue” by Christian Early
  • “Knowing Ourselves as Embodied, Embedded, and Relationally Extended” by Warren S. Brown


A New Edition of The New England Journal of Medicine Is Now Available

Fri, 12/01/2017 - 09:00

The New England Journal of Medicine (vol. 377, no. 12, 2017) is available online by subscription only.

Articles include:

  • “Tuberculosis Elimination in the United States — The Need for Renewed Action” by R. Bayer and K.G. Castro
  • “The Fate of FDA Postapproval Studies” by S. Woloshin, L.M. Schwartz, B. White, and T.J. Moore


A New Edition of Birth: Issues in Prenatal Care Is Now Available

Fri, 12/01/2017 - 09:00

Birth (vol. 44, no. 3, 2017) is available online by subscription only.

Articles include:

  • “Informed Consent and Refusal in Obstetrics: A Practical Ethical Guide” by Andrew Kotaska


A New Edition of Journal of Value Inquiry Is Now Available

Fri, 12/01/2017 - 09:00

Journal of Value Inquiry (vol. 51, no. 3, 2017) is available online by subscription only.

Articles include:

  • “The Ethics of Patenting the BRCA Genes for Breast Cancer Research” by John Jung Park
  • “Focusing Respect on Creatures” by Elizabeth Foreman


A New Edition of Medicine, Health Care and Philosophy Is Now Available

Fri, 12/01/2017 - 09:00

Medicine, Health Care and Philosophy (vol. 20, no. 1, 2017) is available online by subscription only.

Articles include:

  • “Bioenhancement of Morality” by Bert Gordijn and Henk ten Have
  • “Compulsory Administration of Oxytocin Does Not Result in Genuine Moral Enhancement” by Vojin Raki?
  • “‘Unnatural’ Thoughts? On Moral Enhancement of the Human Animal” by Norman K. Swazo
  • “Inspectors’ Ethical Challenges in Health Care Regulation: A Pilot Study” by W. Seekles et al.
  • “Tragedy in Moral Case Deliberation” by Benita Spronk, Margreet Stolper, and Guy Widdershoven
  • “Do We Have a Moral Responsibility to Compensate for Vulnerable Groups? A Discussion on the Right to Health for LGBT People” by Perihan Elif Ekmekci
  • “Personal Factors Affecting Ethical Performance in Healthcare Workers During Disasters and Mass Casualty Incidents in Iran: A Qualitative Study” by Mehrzad Kiani
  • “Withdrawal of Artificial Nutrition and Hydration in Neonatal Intensive Care: Parents’ and Healthcare Practitioners’ Views” by Véronique Fournier et al.
  • “Blurring Nature at Its Boundaries. Vague Phenomena in Current Stem Cell Debate” by Martin Hähnel
  • “Caregiver Burden and the Medical Ethos” by Karsten Witt, Johanne Stümpel, and Christiane Woopen
  • “Suffering and Dying Well: On the Proper Aim of Palliative Care” by Govert den Hartogh
  • “Is Decision-Making Capacity an “Essentially Contested” Concept in Pediatrics?” by Eva De Clercq
  • “Zika, Public Health, and the Distraction of Abortion” by Thana Christina de Campos
  • “Abortion for Fetal Defects: Two Current Arguments” by Susana Nuccetelli


The Mysterious Return of Scarlet Fever

Thu, 11/30/2017 - 15:39

(Vox) – Scarlet fever, a leading killer of children in the 19th and early 20th centuries, is suddenly making a comeback in many parts of the world, and no one knows why. The bacterial infection brings on a red, sandpapery rash all over the body, a high fever, and sore throat, and can cause serious health complications, including heart and kidney damage. The advent of antibiotics in the mid-20th century made the disease less deadly.

Come for a New Hip, Stay for Sea World? San Diego Bets on Medical Tourism

Thu, 11/30/2017 - 15:22

(STAT News) – It’s got sun, sand, top-flight biomedical research, and highly rated hospitals. But can San Diego really become a hub for medical tourism? City leaders sure hope so. They recently launched a marketing initiative — funded mostly by a local philanthropist — that aims to attract patients from across the country and around the world. The pitch: Get your hip replaced or your cancer treated by top specialists — and then take your family to Legoland or SeaWorld.